International comparison of pediatric diabetes registries

Advances in paediatric type 1 diabetes management and increased use of diabetes technology have led to improvements in glycaemia, reduced risk of severe hypoglycemia, and improved quality of life. Since 1993, progressively lower HbA1c targets have been set. The aim of this study was to perform a longitudinal analysis of HbA1c, treatment regimens and acute complications between 2013 and 2022 using data from eight national and one international paediatric diabetes registries.

In this longitudinal analysis, we obtained data from the Australian Diabetes Network, Czech National Childhood Diabetes Registry,Danish Registry of Childhood and Adolescent Diabetes, Diabetes Prospective Follow-up Registry, Norwegian Childhood Diabetes Registry, England and Wales`National Paediatric Diabetes Audit, Swedish Childhood Diabetes Registry, T1D Exchange Quality Improvement Collaborative, and the SWEET initiative. All children (aged >18 years) with T1D with a duration of longer than 3 months were included.

News from 2024

Oral presentation at ADA (American Diabetes Association) June 2024, Orlando, FL, USA

329 – OR

Anthony T. Zimmermann et al.

Dynamics of treatment regimens and glycemic outcomes in > 100,000 children from international pediatric diabetes registries

Publications 2024

A. Zimmermann, S. Lanzinger, S.J. Kummernes, N.A. Lund-Blix, R.W. Holl, E. Frohlich, D.M. Maahs, O. Ebekozien, S. Rompicherla, J.T Warner, S.P. Perez, H. Robinson, M.E. Craig, S. Johnson, K. Akesson, A. Thoren, K. Eeg-Olofsson, A. G. Ranjan, M. Madsen, M. Witsch, H. Bratke, T. Alonso, Z. Sumnik, V. Neuman, O. Cinek, T. Skrivarhaug, J. Svensson

Treatment regimens and glycaemic outcomes in more than 100 000 children with type 1 diabetes (2013-22): a longitudinal analysis of data from paediatric diabetes registries

Lancet Diabetes Endocrinol. Epub 2024 Nov 29. doi: 10.1016/S2213-8587(24)00279-1. PMID: 39622257

Primary Investigator

From Norway: Torild Skrivarhaug, M.D., Professor, Norwegian Childhood Diabetes Registry, Division of Childhood and Adolescent Medicine, Oslo University Hospital / University of Oslo

Co-investigators/participants

  • Anthony T. Zimmermann, Division of Medicine, Lyell McEwin Hospital, Adelaide, SA, Australia

  • Stefanie Lanzinger and Reinhard Holl; Institute of Epidemiology and Medical Biometry, Ulm University, Ulm and German Center for Diabetes Research, Munich, Germany

  • Elke FrÖlich-Reiterer, Dep. of Paediatric and Adolescent Medicine, University of Graz, Austria

  • David M. Maahs, Dep. of Pediatrics, Stanford University School of Medicine, California, USA

  • Osagie Ebekozien and Saketh Rompicherla, T1D Exchange, Boston, MA, USA

  • Justin T. Warner and Saira Pons Perez, National Paediatric Diabetes Audit, Royal College of Paediatrics and Child Health, London, UK

  • Holly Robinson

  • Maria E Craig, University of Sydney; Stephanie Johnson, Queensland Children`s Hospital, Brisbane; Holly Robinson, University of New South Wales, Sydney, Australia

  • Karin Akesson, Alexander Thoren, Katarina Eeg-Olofsson: The Swedish National Diabetes Register; Center of Registries, Gothenburg, Sweden

  • Michael Witsch,Centre Hospitalier de Luxembourg, Luxembourg City, Luxenbourg

  • Heiko Bratke, Haugesund sykehus, Haugesund; Siv Janne Kummernes og Nicolai A. Lund-Blix, Oslo University Hospital, Oslo, Norway

  • Todd Alonso, Barabara Davis center, University of Colorado, USA

  • Zdenek Sumnik, Vit Neuman, Andrej Cinek, Dep. Of Pedatrics, Faculty of Medicine, Charles University, Prague, Czehia

  • Jannet Svensson and Ajenthen G Ranjan, Sten Diabetes Center, Copenhagen, Herlev; Mette Madsen, Steno Diabetes Center North, Denmark