Type 2 diabetes and metabolism

by Kåre I. Birkeland Group

1.      The DAPHNE- , DISCOVER- and DIAFLU studies are large epidemiological register studies of type 2 diabetes in Norway. We are also involved in a substudy of HUNT 2 and 3 focusing on anthropometric indices and subsequent risk of cardiovascular events.

2.      A genetic/epigenetic sub-project under the STORK and STORK-Groruddalen studies.

3.      The 4B study: The effect of bariatric surgery on bone marrow fat and glucose metabolism in morbid obese subjects with and without type 2 diabetes.

4.      Subprojects under the MyoGlu-study – A controlled, intervention study of high-intensive exercise training in subjects with abnormal glucose tolerance and controls.

5.      The HypoAlert-study – An experimental study of subjects with type 1 diabetes and hypoglycemia unawareness to test new hypoglycemia alert devices using hypo- and euglycaemic glucose clamp techniques.

6.      The FIBERDIA – a randomized controlled trial of the effects of probiotica on incretin responses in type 2 diabetes.

7.      10 year follow up of subjects after bariatric surgery with focus on the prevalence of diabetes and metabolic risk factors.

8.      Several multi-center phase II, III and IV clinical trials in collaboration with the pharmaceutical industry.