Immunogenetics and epigenetics of autoimmune diseases

by Benedicte Lie and Dag E. Undlien Group

  1. Correlation between genetic risk variants for type 1 diabetes and other autoimmune diseases and their gene expression in the immunologically important thymus
  2. Exploring and characterizing the HLA complex, the most important genetic contributor to type 1 diabetes and other autoimmune diseases.
  3. Differences and similarities between HLA risk profile to type 1 diabetes and celiac diseases for individuals with both diagnosis
  4. Exploring genetic and environmental risk  factors, and their interactions, in rheumatoid arthritis, an autoimmune disease sharing many risk factors with type 1 diabetes